HCA57 Antibody, ALEXA FLUOR 555

HCA57 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES

Price 332

Size 100ul

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Long name	ALEXA FLUOR 555 Conjugated, HCA57 Polyclonal Antibody
Also known as	Anti-HCA57 PAb ALEXA FLUOR 555
Category	Conjugated Primary Antibodies
Conjugated with	555, ALEXA FLUOR®
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	HCA57
Specificity	This is a highly specific antibody against HCA57
Modification	Unmodified
Modification Site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TID1/HCA57
Gene ID Number	9093
Tested applications	IF(IHC-P)
Recommended dilutions	IF(IHC-P)(1:50-200)
Crossreactivity	Mouse, Rat, Human
Cross-reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen	A J domain mutant of hTid1L can dominantly suppress apoptosis and in sharp contrast the J domain mutant of hTid1S increases apoptosis, Expression of hTid1L increases apoptosis induced by DNA damaging agents as mitomycin C and TNF alpha, Expression of hTid1S and hTid1L affects cytochrome c release from the mitochondria and caspase 3 activation, Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals, It is strongly suggested that these two splice variants exert their anti and pro apoptotic effects through discrete substrates and activities, These proteins are the conserved members of the DnaJ family of proteins which act as cochaperons for mitochondrial Hsp70, They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity, while activation of caspase 8 is unaffected, TID1 is a human homolog of the Drosophila tumor suppressor lethal tumerous imaginal discs and encodes two mitochondrial matrix localized splice variants of human Tid1 designated hTid1S and hTid1L
Purification	Purified by Protein A
Storage conditions	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission	553nm/568nm
Synonyms	DNJA3_HUMAN, DnaJ homolog subfamily A member 3 mitochondrial precursor, DnaJ protein Tid 1, DnaJ protein Tid1, HCA57, Hepatocellular carcinoma associated antigen 57, Highly similar to HYPOTHETICAL 105, III [Caenorhabditis elegans], TID1, Tumorous imaginal discs Drosophila homolog, Tumorous imaginal discs protein Tid56 homolog, hTid 1, hTid1, 5 IN CHROMOSOME, 9 KD PROTEIN F22B7, DnaJ Hsp40 homolog subfamily A member 3
Properties	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation	ALEXA FLUOR 555, Alexa Fluor
Gene target	HCA57
Short name	HCA57 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Label	ALEXA FLUOR 555
Alternative name	ALEXA FLUOR 555, HCA57 (Antibody to)
Alternative technique	antibodies

HCA57 Antibody, ALEXA FLUOR 555

HCA57 Antibody, ALEXA FLUOR 555 size: 100ul 332

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