HCA57 Antibody, Cy3 Conjugated

HCA57 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 350

Size 0.1ml

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Long name	Cy3 Conjugated, HCA57 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	cy3 conjugation kit
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	HCA57
Specificity	This is a highly specific antibody against HCA57
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human TID1/HCA57
Gene ID number	9093
Tested applications	IF(IHC-P)
Recommended dilutions	IF(IHC-P)(1:50-200)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	A J domain mutant of hTid1L can dominantly suppress apoptosis and in sharp contrast the J domain mutant of hTid1S increases apoptosis, Expression of hTid1L increases apoptosis induced by DNA damaging agents as mitomycin C and TNF alpha, Expression of hTid1S and hTid1L affects cytochrome c release from the mitochondria and caspase 3 activation, Hence the relative abundance of these proteins or their substrates may allow the mitochondria to dampen or enhance the apoptotic signals, It is strongly suggested that these two splice variants exert their anti and pro apoptotic effects through discrete substrates and activities, These proteins are the conserved members of the DnaJ family of proteins which act as cochaperons for mitochondrial Hsp70, They contain a conserved tetrahedrical J domain which binds to Hsp70 chaperones and activates their ATPase activity, while activation of caspase 8 is unaffected, TID1 is a human homolog of the Drosophila tumor suppressor lethal tumerous imaginal discs and encodes two mitochondrial matrix localized splice variants of human Tid1 designated hTid1S and hTid1L
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	512, 550nm/570, 615nm
Synonyms	DNJA3_HUMAN, DnaJ homolog subfamily A member 3 mitochondrial precursor, DnaJ protein Tid 1, DnaJ protein Tid1, HCA57, Hepatocellular carcinoma associated antigen 57, Highly similar to HYPOTHETICAL 105, III [Caenorhabditis elegans], TID1, Tumorous imaginal discs Drosophila homolog, Tumorous imaginal discs protein Tid56 homolog, hTid 1, hTid1, 5 IN CHROMOSOME, 9 KD PROTEIN F22B7, DnaJ Hsp40 homolog subfamily A member 3
Properties	1 of the HCA57 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	HCA57 Conjugated
Short name	Conjugated, HCA57 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Cy3
Alternative name	cyanine 3 coupled, HCA57 (Antibody to)
Alternative technique	antibodies

HCA57 Antibody, Cy3 Conjugated

HCA57 Antibody, Cy3 Conjugated size: 0.1ml 350

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