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HCK (1508CT602.13.1) Monoclonal Antibody

HCK (1508CT602.13.1) Monoclonal Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name1) Monoclonal Antibody, 13, HCK (1508CT602
Also known as1) Monoclonal Antibody, 13, HCK (1508CT602
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHCK
SpecificityThis is a highly specific antibody against HCK
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1, 13, 1508CT602
SourceThis HCK antibody is generated from a mouse immunized with a recombinant protein of human HCK
Gene ID number3055
Swiss ProtP08631
Tested Applications IF, WB
Recommended dilutions WB(1:2000-1:4000), IF(1:25)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts downstream of receptors that bind the Fc region of immunoglobulins, BCR, During the phagocytic process, ELMO1, FCGR2A, GAB1, GAB2, IL2, IL6 and IL8, Inhibits TP73-mediated transcription activation and TP73-mediated apoptosis, PLAUR, Phosphorylates ADAM15, Phosphorylates CBL in response to activation of immunoglobulin gamma Fc region receptors, Plays a role in the release of inflammatory molecules, Promotes reorganization of the actin cytoskeleton and actin polymerization, RAPGEF1, STAT5B, TP73, VAV1 and WAS, and activation of NADPH oxidase to bring about the respiratory burst, and integrins, but also CSF3R, cell adhesion and migration, cell survival and proliferation, degranulation, formation of podosomes and cell protrusions, including neutrophil, macrophage and mast cell functions, mediates mobilization of secretory lysosomes, monocyte, phagocytosis, such as FCGR1A and FCGR2A, such as ITGB1 and ITGB2, the receptors for IFNG, Non-receptor tyrosine-protein kinase found in hematopoietic cells that transmits signals from cell surface receptors and plays an important role in the regulation of innate immune responses
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HCK, Hematopoietic cell kinase, Hemopoietic cell kinase, Tyrosine-protein kinase HCK, p59-HCK/p60-HCK, p59Hck, p61Hck, JTK9
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target1) Monoclonal, 13, HCK (1508CT602
Short name1) Monoclonal Antibody, 13, HCK (1508CT602
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name1) monoclonal (Antibody to), 13, hemopoietic cell kinase (1508CT602
Alternative techniqueantibodies
Alternative to gene target BT, HCK and IDBG-64463 and ENSG00000101336 and 3055, Hck and IDBG-209984 and ENSMUSG00000003283 and 15162, JTK9 and p59Hck and p61Hck, nuclei, this GO :0002522 and leukocyte migration involved in immune response and biological process this GO :0002758 and innate immune response-activating signal transduction and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005764 and lysosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005884 and actin filament and cellular component this GO :0005901 and caveola and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006909 and pha this GO cytosis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007498 and mesoderm development and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008360 and regulation of cell shape and biological process this GO :0016032 and viral process and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004715: non-membrane spanning protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004715: non-membrane spanning protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030133 and transport vesicle and cellular component this GO :0030838 and positive regulation of actin filament polymerization and biological process this GO :0031234 and extrinsic component of cytoplasmic side of plasma membrane and cellular component this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042995 and cell projection and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043299 and leukocyte degranulation and biological process this GO :0045087 and innate immune response and biological process this GO :0045728 and respiratory burst after pha this GO cytosis and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050764 and regulation of pha this GO cytosis and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0071801 and regulation of podosome assembly and biological process this GO :2000251 and positive regulation of actin cytoskeleton reorganization and biological process, 44996 and IDBG-641612 and ENSBTAG00000007932 and 280814, hemopoietic cell kinase
Identity 4840
Gene HCK
Long gene name HCK proto-oncogene, Src family tyrosine kinase
Synonyms gene name hemopoietic cell kinase
Synonyms JTK9
Locus 20q11, 21
Discovery year 1986-01-01
GenBank acession AK026432
Entrez gene record 3055
Pubmed identfication 3496523
Classification SH2 domain containing Src family tyrosine kinases
Havana BLAST/BLAT OTTHUMG00000032204

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