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HCN3 Antibody, Biotin Conjugated

HCN3 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, HCN3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHCN3
SpecificityThis is a highly specific antibody against HCN3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human HCN3
Gene ID number57657
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background HCN channels are expressed in the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, HCN3 contains a segment characterized by a series of positively charged amino acids at every third position, In the brain, The HCN family consists of four members (HCN1-4), The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart, This region designated S4 is likely to be the voltage sensor of the protein, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides, each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif, heart, respectively, thalamus and testis, Hyperpolarization-activated
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms KIAA1535
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHCN3 Conjugated
Short name Conjugated, HCN3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, HCN3 (Antibody to)
Alternative techniqueantibodies
Identity 19183
Gene HCN3
Long gene name hyperpolarization activated cyclic nucleotide gated potassium channel 3
Synonyms gene name hyperpolarization activated cyclic nucleotide-gated potassium channel 3
Locus 1q22
Discovery year 2002-09-02
GenBank acession AB040968
Entrez gene record 57657
Pubmed identfication 16382102
RefSeq identity NM_020897
Classification Cyclic nucleotide gated channels
Havana BLAST/BLAT OTTHUMG00000035872

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