Name : HCN3 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6689986510
| Long name | Biotin Conjugated, HCN3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HCN3 |
| Specificity | This is a highly specific antibody against HCN3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human HCN3 |
| Gene ID number | 57657 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | HCN channels are expressed in the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, HCN3 contains a segment characterized by a series of positively charged amino acids at every third position, In the brain, The HCN family consists of four members (HCN1-4), The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart, This region designated S4 is likely to be the voltage sensor of the protein, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides, each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif, heart, respectively, thalamus and testis, Hyperpolarization-activated |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | KIAA1535 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HCN3 Conjugated |
| Short name | Conjugated, HCN3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, HCN3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19183 |
| Gene | HCN3 |
| Long gene name | hyperpolarization activated cyclic nucleotide gated potassium channel 3 |
| Synonyms gene name | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 |
| Locus | 1q22 |
| Discovery year | 2002-09-02 |
| GenBank acession | AB040968 |
| Entrez gene record | 57657 |
| Pubmed identfication | 16382102 |
| RefSeq identity | NM_020897 |
| Classification | Cyclic nucleotide gated channels |
| Havana BLAST/BLAT | OTTHUMG00000035872 |