Name : HCN3 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN3747822545
| Long name | FITC Conjugated, HCN3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HCN3 |
| Specificity | This is a highly specific antibody against HCN3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human HCN3 |
| Gene ID number | 57657 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | HCN channels are expressed in the brain, HCN3 and HCN4 exhibit subcortical distribution mainly concentrated in the hypothalamus and thalamus, HCN3 contains a segment characterized by a series of positively charged amino acids at every third position, In the brain, The HCN family consists of four members (HCN1-4), The pacemaker properties of HCN channels contribute to spontaneous rhythmic activity in the brain and heart, This region designated S4 is likely to be the voltage sensor of the protein, cyclic nucleotide-binding channels (HCN) are voltage-gated cation channels that are activated by direct binding of intracellular cyclic nucleotides, each with a core transmembrane segment domain and a C-terminal 120 amino-acid cyclic nucleotide-binding domain motif, heart, respectively, thalamus and testis, Hyperpolarization-activated |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | KIAA1535 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HCN3 Conjugated |
| Short name | FITC Conjugated, HCN3 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, HCN3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19183 |
| Gene | HCN3 |
| Long gene name | hyperpolarization activated cyclic nucleotide gated potassium channel 3 |
| Synonyms gene name | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 |
| Locus | 1q22 |
| Discovery year | 2002-09-02 |
| GenBank acession | AB040968 |
| Entrez gene record | 57657 |
| Pubmed identfication | 16382102 |
| RefSeq identity | NM_020897 |
| Classification | Cyclic nucleotide gated channels |
| Havana BLAST/BLAT | OTTHUMG00000035872 |