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HCV Core protein Antibody, ALEXA FLUOR 594

HCV Core protein Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, HCV Core protein Polyclonal Antibody
Also known asAnti-HCV Core protein PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHCV Core protein
SpecificityThis is a highly specific antibody against HCV Core protein
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/3011
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HCV-Core
Swiss ProtP26664
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityVirus
Cross-reactive species detailsHCV
Background of the antigen Also regulates many host cellular functions such as signaling pathways and apoptosis, Also represses cell cycle negative regulating factor CDKN1A, Enhances TRAIL mediated apoptosis, Interacts with, May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage, May repress the promoter of p53, May suppress the human FOS and HIV-1 LTR activity, May transactivate human MYC, Mediates apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit, Plays an important role in virus-mediated cell transformation leading to hepatocellular carcinomas, Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation, Rous sarcoma virus LTR, Secreted core protein is able to bind C1QR1 at the T-cell surface, Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, although its effect on death receptors-induced apoptosis remains controvertial, and SV40 promoters, and activates AP-1, and activates STAT3 leading to cellular transformation, and promotes virion budding, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm, resulting in down-regulation of T-lymphocytes proliferation, suggesting that it might play a role in immune-mediated liver cell injury, suggesting that it might play a role in mediated apoptosis, thereby interrupting an important check point of normal cell cycle regulation, Core protein packages viral RNA to form a viral nucleocapsid
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms Core protein p21, Core protein p9, HCV core protein, HCV-Core protein, HCVAg, Hepatitis C Virus Core Antigen-C, Hepatitis C Virus core protein, capsid protein, polyprotein precursor, Core protein p19, HCV core antigen
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene 2, 3, 4, 5, HCV Core antigens or envelope proteins are used for immunization to obtain diagnostic antibodies, Hepatitis C virus is the cause of , NS genotypes 1, NS4, are small (55&ndash,  ,  , (HCV) NS3, (Hepatocellular carcinoma , 65 , Hepatitis C virus , Liver Cancer , RNA viruses, abbreviated HCC) and , and some cancers such as , enveloped, hepatitis C , in humans, in size), lymphomas , nm , positive-sense , single-stranded 
Gene targetHCV Core protein
Short nameHCV Core protein Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Hepatitis C virus Core protein (Antibody to)
Alternative techniqueantibodies

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