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HCV-NS3 Antibody, Biotin Conjugated

HCV-NS3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, HCV-NS3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHCV-NS3
SpecificityThis is a highly specific antibody against HCV-NS3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1400-1550/3010
SourceKLH conjugated synthetic peptide derived from human HCV-NS3
Swiss ProtQ9WMX2
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityVirus
Crossreactive species detailsHCV
Antigen background Also regulates many host cellular functions such as signaling pathways and apoptosis, Also represses cell cycle negative regulating factor CDKN1A, Enhances TRAIL mediated apoptosis, Interacts with, May alter lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage, May repress the promoter of p53, May suppress the human FOS and HIV-1 LTR activity, May transactivate human MYC, Mediates apoptotic pathways throught association with TNF-type receptors TNFRSF1A and LTBR, Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit, Plays an important role in virus-mediated cell transformation leading to hepatocellular carcinomas, Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation, Rous sarcoma virus LTR, Secreted core protein is able to bind C1QR1 at the T-cell surface, Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses NK-kappaB activation, although its effect on death receptors-induced apoptosis remains controvertial, and SV40 promoters, and activates AP-1, and activates STAT3 leading to cellular transformation, and promotes virion budding, and sequester CREB3 and SP110 isoform3/Sp110b in the cytoplasm, resulting in down-regulation of T-lymphocytes proliferation, suggesting that it might play a role in immune-mediated liver cell injury, suggesting that it might play a role in mediated apoptosis, thereby interrupting an important check point of normal cell cycle regulation, Core protein packages viral RNA to form a viral nucleocapsid
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Hepacivirin, NS3P, POLG_HCVBK, Serine protease NS3
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene 2, 3, 4, 5, HCV Core antigens or envelope proteins are used for immunization to obtain diagnostic antibodies, Hepatitis C virus is the cause of , NS genotypes 1, NS4, are small (55&ndash,  ,  , (HCV) NS3, (Hepatocellular carcinoma , 65 , Hepatitis C virus , Liver Cancer , RNA viruses, abbreviated HCC) and , and some cancers such as , enveloped, hepatitis C , in humans, in size), lymphomas , nm , positive-sense , single-stranded 
Gene targetHCV-NS3 Conjugated
Short name Conjugated, HCV-NS3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Hepatitis C virus-NS3 (Antibody to)
Alternative techniqueantibodies

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