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HDAC8 Antibody, FITC Conjugated

HDAC8 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, HDAC8 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHDAC8
SpecificityThis is a highly specific antibody against HDAC8
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range180-230/377
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human HDAC8
Gene ID number55869
Swiss ProtQ9BY41
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin, H2B, H3 and H4), Histone deacetylases act via the formation of large multiprotein complexes, Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, May play a role in smooth muscle cell contractility, cell cycle progression and developmental events, Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms RPD3
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHDAC8 Conjugated
Short name FITC Conjugated, HDAC8 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, HDAC8 (Antibody to)
Alternative techniqueantibodies
Identity 13315
Gene HDAC8
Long gene name histone deacetylase 8
Synonyms gene HDACL1 WTS MRXS6
Synonyms gene name histone deacetylase-like 1 Wilson-Turner X-linked mental retardation syndrome
Locus Xq13, 1
Discovery year 2000-11-28
GenBank acession AF230097
Entrez gene record 55869
Pubmed identfication 10756090 10922473 22889856
RefSeq identity NM_018486
Classification X-linked mental retardation Histone deacetylases, class I
Havana BLAST/BLAT OTTHUMG00000021814
Locus Specific Databases Mental Retardation database

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