Name : HDAC8 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN7857264035
| Long name | FITC Conjugated, HDAC8 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HDAC8 |
| Specificity | This is a highly specific antibody against HDAC8 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 180-230/377 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human HDAC8 |
| Gene ID number | 55869 |
| Swiss Prot | Q9BY41 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin, H2B, H3 and H4), Histone deacetylases act via the formation of large multiprotein complexes, Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, May play a role in smooth muscle cell contractility, cell cycle progression and developmental events, Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | RPD3 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HDAC8 Conjugated |
| Short name | FITC Conjugated, HDAC8 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, HDAC8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13315 |
| Gene | HDAC8 |
| Long gene name | histone deacetylase 8 |
| Synonyms gene | HDACL1 WTS MRXS6 |
| Synonyms gene name | histone deacetylase-like 1 Wilson-Turner X-linked mental retardation syndrome |
| Locus | Xq13, 1 |
| Discovery year | 2000-11-28 |
| GenBank acession | AF230097 |
| Entrez gene record | 55869 |
| Pubmed identfication | 10756090 10922473 22889856 |
| RefSeq identity | NM_018486 |
| Classification | X-linked mental retardation Histone deacetylases, class I |
| Havana BLAST/BLAT | OTTHUMG00000021814 |
| Locus Specific Databases | Mental Retardation database |