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Heparanase Antibody

Heparanase Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHeparanase Primary Polyclonal Antibody
Also known asHeparanase PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHeparanase
SpecificityThis is a highly specific antibody against Heparanase
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Heparanase
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Heparanase is a heterodimer comprised of a 50 kDa subunit harboring the active site and an 8 kDa subunit, Heparanase is highly expressed in myeloid leukocytes (i, Heparanase plays an important role in ECM degradation, Human heparanase was found to be upregulated in various types of primary tumors, It is produced as a latent 65 kDa precursor and proteolytically processed to its active form, Upon degradation, correlating in some cases with increased tumor invasiveness and vascularity and with poor prospective survival, facilitating the migration and extravasations of tumor cells and inflammatory leukocytes, heparanase releases growth factors and cytokines that stimulate cell proliferation and chemotaxis, neutrophils) in platelets and in human placenta, which degrades heparan sulfate side chains of heparan sulfate proteoglycans (HSPGs) in the extracellular matrix, Heparanase is an endo-beta-D-glucuronidase, e
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Endo glucoronidase, Endo glucoronidase, Endo-glucoronidase, HEP, HPA, HPR 1, HPR1, HPSE, HPSE 1, HPSE1, HPSE_HUMAN, HSE 1, HSE1, Heparanase 1, Heparanase1, Hpa 1, Hpa1, heparanase, heparanase 1, heparanase-1, heparanase1, Heparanase 50 kDa subunit
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHeparanase
Short nameHeparanase Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHeparanase (Antibody to)
Alternative techniqueantibodies
Identity 12521
Gene UFS
Long gene name heparanase 2 (inactive)
Synonyms gene name urofacial syndrome heparanase 2
Synonyms HPA2 HPR2 HPSE2
Locus 10q24, 2
Discovery year 2002-09-02
GenBank acession AF282885
Entrez gene record 60495
Pubmed identfication 11027606 20560210 9199567 20576607
RefSeq identity NM_021828
Havana BLAST/BLAT OTTHUMG00000018880

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