Filters

Heparanase Antibody, Biotin Conjugated

Heparanase Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, Heparanase Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHeparanase
SpecificityThis is a highly specific antibody against Heparanase
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Heparanase
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Heparanase is a heterodimer comprised of a 50 kDa subunit harboring the active site and an 8 kDa subunit, Heparanase is highly expressed in myeloid leukocytes (i, Heparanase plays an important role in ECM degradation, Human heparanase was found to be upregulated in various types of primary tumors, It is produced as a latent 65 kDa precursor and proteolytically processed to its active form, Upon degradation, correlating in some cases with increased tumor invasiveness and vascularity and with poor prospective survival, facilitating the migration and extravasations of tumor cells and inflammatory leukocytes, heparanase releases growth factors and cytokines that stimulate cell proliferation and chemotaxis, neutrophils) in platelets and in human placenta, which degrades heparan sulfate side chains of heparan sulfate proteoglycans (HSPGs) in the extracellular matrix, Heparanase is an endo-beta-D-glucuronidase, e
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Endo glucoronidase, Endo glucoronidase, Endo-glucoronidase, HEP, HPA, HPR 1, HPR1, HPSE, HPSE 1, HPSE1, HPSE_HUMAN, HSE 1, HSE1, Heparanase 1, Heparanase1, Hpa 1, Hpa1, heparanase, heparanase 1, heparanase-1, heparanase1, Heparanase 50 kDa subunit
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHeparanase Conjugated
Short name Conjugated, Heparanase Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Heparanase (Antibody to)
Alternative techniqueantibodies

Subscribe to our Newsletter