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HER2 receptor(NT) Antibody

HER2 receptor(NT) Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHER2 receptor(NT) Primary Polyclonal Antibody
Also known asHER2 receptor(NT) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHER2 receptorNT
SpecificityThis is a highly specific antibody against HER2 receptorNT
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HER2 receptor
Gene ID number2064
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, Alternative splicing results in several additional transcript variants, Amplification and/or overexpression of this gene has been reported in numerous cancers, However, Ile654/Ile655, Jul 2008], This protein has no ligand binding domain of its own and therefore cannot bind growth factors, [provided by RefSeq, including breast and ovarian tumors, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, shown here, some encoding different isoforms and others that have not been fully characterized, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase, with the most common allele, This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C erbB 2, C-erbB2, CD340, CerbB2, ERBB2_HUMAN, Erb B2, Erbb2 protein, HER 2, HER 2/neu, HER2, HER2 receptor, Her2/neu, Herstatin, MLN 19, MLN19, Metastatic lymph node gene 19 protein, NEU, NEU Proto Oncogene, NGL, Neuro Glioblastoma Derived Oncogene Homolog, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Receptor Protein Tyrosine Kinase ErbB2 Precursor, Receptor tyrosine protein kinase erbB 2, Receptor tyrosine-protein kinase erbB-2, TKR1, Tyrosine kinase type cell surface receptor HER2, c erb B2, erbb2, p185 ErbB2, p185erbB2, v erb b2 erythroblastic leukemia viral oncogene homolog 2 neuro/glioblastoma derived oncogene homolog avian, erbB-2 isoform 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetHER2 receptor(NT)
Short nameHER2 receptor(NT) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHER2 receptor(NT) (Antibody to)
Alternative techniqueantibodies
Identity 3430
Gene ERBB2
Long gene name erb-b2 receptor tyrosine kinase 2
Synonyms gene NGL
Synonyms gene name v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
Synonyms NEU HER-2 CD340 HER2
Synonyms name neuro/glioblastoma derived oncogene homolog human epidermal growth factor receptor 2
Locus 17q12
Discovery year 2001-06-22
GenBank acession X03363
Entrez gene record 2064
RefSeq identity NM_004448
Classification CD molecules Minor histocompatibility antigens Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT OTTHUMG00000179300
Locus Specific Databases LRG_724

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