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HER4 (Tyr1188) Antibody, FITC Conjugated

HER4 (Tyr1188) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, HER4 (Tyr1188) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHER4 Tyr1188
SpecificityThis is a highly specific antibody against HER4 Tyr1188
ModificationPhosphorylation
Modification siteTyr1188
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1188
Gene ID number2066
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alternatively spliced variants which encode different protein isoforms have been described, It encodes a single-pass type I membrane protein with multiple cysteine rich domains, Jul 2008], Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment, Mutations in this gene have been associated with cancer, The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation, [provided by RefSeq, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif, a transmembrane domain, a tyrosine kinase domain, however, not all variants have been fully characterized, This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ALS19 HER4
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHER4 (Tyr1188) Conjugated
Short name FITC Conjugated, HER4 (Tyr1188) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, HER4 (Tyr1188) (Antibody to)
Alternative techniqueantibodies
Identity 3432
Gene ERBB4
Long gene name erb-b2 receptor tyrosine kinase 4
Synonyms gene name v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Synonyms name human epidermal growth factor receptor 4
Locus 2q34
Discovery year 1995-09-07
GenBank acession L07868
Entrez gene record 2066
Pubmed identfication 7700649 17018285
RefSeq identity NM_001042599
Classification Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT OTTHUMG00000133012

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