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HES3 Antibody, Cy5.5 Conjugated

HES3 Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, HES3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHES3
SpecificityThis is a highly specific antibody against HES3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human HES3
Gene ID number390992
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background HES1 and HES2 are expressed in a variety of adult and embryonic tissues, HES1-6, HES2 binds to both N and E box sites, HES3 is expressed exclusively in cerebellar Purkinje cells, HES6 inhibits HES1 activity, HES6 is produced in brain as well as in the limb buds of developing embryos, Most HES family members, Rather, The HES family members form a complex with TLE, The HES/TLE complex functions by directly binding to DNA, The mammalian homologues of Drosophila hairy and Enhancer of split are the HES gene family members, and HES5 is found solely in the nervous system, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins, including HES1 and HES5, instead of interfering with activator proteins, preferentially bind to the N box (CACNAG) as opposed to the E box (CANNTG), the mammalian homologue of Groucho, thereby promoting transcription, which also encode bHLH transcriptional repressors that regulate myogenesis and neurogenesis, while HES6 does not bind DNA, The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms bHLHb43
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetHES3 Conjugated
Short name Conjugated, HES3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, HES3 (Antibody to)
Alternative techniqueantibodies
Identity 26226
Gene HES3
Long gene name hes family bHLH transcription factor 3
Synonyms gene name hairy and enhancer of split 3 (Drosophila)
Locus 1p36, 31
Discovery year 2005-05-17
Entrez gene record 390992
RefSeq identity NM_001024598
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000001271

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