Filters

HEXA/Beta hexosaminidase subunit alpha Antibody

HEXA/Beta hexosaminidase subunit alpha Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHEXA/Beta hexosaminidase subunit alpha Antibody
Also known asHEXA/Beta hexosaminidase subunit alpha Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHEXA/Beta hexosaminidase subunit alpha
SpecificityThis is a highly specific antibody against HEXA/Beta hexosaminidase subunit alpha
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Beta hexosaminidase subunit alpha
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A mutation in the &, HEXA, TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides, The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS, along with the cofactor CM2 activator protein, also designated beta-Hexosaminidase A, also known as GM2-gangliosidosis type I, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues, chain, is a trimer composed of one &, one â, subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), &circ, &circ, «, «, -A chain and one â, -B chain and is found in the lysosomes of cells, Hexosaminidase A (HEXA), aring, aring
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Beta N acetylhexosaminidase, Beta N acetylhexosaminidase subunit alpha, Beta hexosaminidase subunit alpha, Beta-N-acetylhexosaminidase subunit alpha, Beta-hexosaminidase subunit alpha, HEXA_HUMAN, Hexa, Hexosaminidase A, Hexosaminidase A alpha polypeptide, Hexosaminidase A alpha polypeptide, Hexosaminidase subunit A, MGC99608, N acetyl beta glucosaminidase, N acetyl beta glucosaminidase subunit alpha, N-acetyl-beta-glucosaminidase subunit alpha, TSD, Beta hexosaminidase alpha chain precursor
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHEXA/Beta hexosaminidase subunit alpha
Short nameHEXA/Beta hexosaminidase subunit alpha Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHEXA/b hexosaminidase functionnal sequence a (Antibody to)
Alternative techniqueantibodies
Identity 4878
Gene HEXA
Long gene name hexosaminidase subunit alpha
Synonyms gene name hexosaminidase A (alpha polypeptide)
Synonyms name Tay Sachs disease GM2 gangliosidosis beta-hexosaminidase subunit alpha
Locus 15q23
Discovery year 2001-06-22
GenBank acession M13520
Entrez gene record 3073
Pubmed identfication 2952641 3013851
RefSeq identity NM_000520
Havana BLAST/BLAT OTTHUMG00000133445
Locus Specific Databases Hexosaminidase A, Tay-Sachs Disease ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Similar products

Subscribe to our Newsletter