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HEXA/Beta hexosaminidase subunit alpha Antibody, ALEXA FLUOR 350

HEXA/Beta hexosaminidase subunit alpha Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, HEXA/Beta hexosaminidase subunit alpha Antibody
Also known asAnti-HEXA/Beta hexosaminidase subunit alpha PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHEXA/Beta hexosaminidase subunit alpha
SpecificityThis is a highly specific antibody against HEXA/Beta hexosaminidase subunit alpha
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Beta hexosaminidase subunit alpha
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A mutation in the &, HEXA, TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides, The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS, along with the cofactor CM2 activator protein, also designated beta-Hexosaminidase A, also known as GM2-gangliosidosis type I, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues, chain, is a trimer composed of one &, one â, subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), &circ, &circ, «, «, -A chain and one â, -B chain and is found in the lysosomes of cells, Hexosaminidase A (HEXA), aring, aring
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetHEXA/Beta hexosaminidase subunit alpha
Short nameHEXA/Beta hexosaminidase subunit alpha Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, HEXA/b hexosaminidase functionnal sequence a (Antibody to)
Alternative techniqueantibodies
Identity 4878
Gene HEXA
Long gene name hexosaminidase subunit alpha
Synonyms gene name hexosaminidase A (alpha polypeptide)
Synonyms name Tay Sachs disease GM2 gangliosidosis beta-hexosaminidase subunit alpha
Locus 15q23
Discovery year 2001-06-22
GenBank acession M13520
Entrez gene record 3073
Pubmed identfication 2952641 3013851
RefSeq identity NM_000520
Havana BLAST/BLAT OTTHUMG00000133445
Locus Specific Databases Hexosaminidase A, Tay-Sachs Disease ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

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