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HEXA/Beta hexosaminidase subunit alpha Antibody, Cy5.5 Conjugated

HEXA/Beta hexosaminidase subunit alpha Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, HEXA/Beta hexosaminidase subunit alpha Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHEXA/Beta hexosaminidase subunit alpha
SpecificityThis is a highly specific antibody against HEXA/Beta hexosaminidase subunit alpha
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Beta hexosaminidase subunit alpha
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A mutation in the &, HEXA, TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides, The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS, along with the cofactor CM2 activator protein, also designated beta-Hexosaminidase A, also known as GM2-gangliosidosis type I, catalyzes the degradation of GM2 ganglioside and other molecules containing terminal N-acetyl hexosamines in the brain and other tissues, chain, is a trimer composed of one &, one â, subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), &circ, &circ, «, «, -A chain and one â, -B chain and is found in the lysosomes of cells, Hexosaminidase A (HEXA), aring, aring
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetHEXA/Beta hexosaminidase subunit alpha Conjugated
Short name Conjugated, HEXA/Beta hexosaminidase subunit alpha Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, HEXA/b hexosaminidase functionnal sequence a (Antibody to)
Alternative techniqueantibodies
Identity 4878
Gene HEXA
Long gene name hexosaminidase subunit alpha
Synonyms gene name hexosaminidase A (alpha polypeptide)
Synonyms name Tay Sachs disease GM2 gangliosidosis beta-hexosaminidase subunit alpha
Locus 15q23
Discovery year 2001-06-22
GenBank acession M13520
Entrez gene record 3073
Pubmed identfication 2952641 3013851
RefSeq identity NM_000520
Havana BLAST/BLAT OTTHUMG00000133445
Locus Specific Databases Hexosaminidase A, Tay-Sachs Disease ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

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