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HEXB Antibody

HEXB Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenHEXB
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the HEXB antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis HEXB antibodyis to be used only for research purposes and not for diagnostics
Gene ID #3074
PurityAntigen affinity
Description Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II), HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity, It is mapped to 5q13, and other molecules containing terminal N-acetyl hexosamines, catalyzes the degradation of the ganglioside GM2, together with the cofactor GM2 activator protein, 3, Hexosaminidase beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene
ImmunogenHuman partial recombinant protein (AA 381-556) was used as the immunogen for this HEXB antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HEXB antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetHEXB
Short nameHEXB Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHEXB (Antibody to)
Alternative techniqueantibodies
Identity 4879
Gene HEXB
Long gene name hexosaminidase subunit beta
Synonyms gene name hexosaminidase B (beta polypeptide)
Synonyms name beta-hexosaminidase subunit beta
Locus 5q13, 3
Discovery year 2001-06-22
GenBank acession M13519
Entrez gene record 3074
Pubmed identfication 2579389 3013851
RefSeq identity NM_000521
Havana BLAST/BLAT OTTHUMG00000102057
Locus Specific Databases HEXB Locus Database

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