Name : HEXB chain A Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN7822805156
| Long name | Biotin Conjugated, HEXB chain A Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HEXB chain A |
| Specificity | This is a highly specific antibody against HEXB chain A |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human HEXB chain A |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II), Beta-hexosaminidase is composed of two subunits, Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases, Jul 2008], Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses, [provided by RefSeq, alpha and beta, and other molecules containing terminal N-acetyl hexosamines, catalyzes the degradation of the ganglioside GM2, together with the cofactor GM2 activator protein, which are encoded by separate genes, Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HEXB chain A Conjugated |
| Short name | Conjugated, HEXB chain A Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, HEXB epitope A (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4879 |
| Gene | HEXB |
| Long gene name | hexosaminidase subunit beta |
| Synonyms gene name | hexosaminidase B (beta polypeptide) |
| Synonyms name | beta-hexosaminidase subunit beta |
| Locus | 5q13, 3 |
| Discovery year | 2001-06-22 |
| GenBank acession | M13519 |
| Entrez gene record | 3074 |
| Pubmed identfication | 2579389 3013851 |
| RefSeq identity | NM_000521 |
| Havana BLAST/BLAT | OTTHUMG00000102057 |
| Locus Specific Databases | HEXB Locus Database |