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HEXB chain A Antibody, Biotin Conjugated

HEXB chain A Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, HEXB chain A Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHEXB chain A
SpecificityThis is a highly specific antibody against HEXB chain A
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human HEXB chain A
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II), Beta-hexosaminidase is composed of two subunits, Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases, Jul 2008], Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses, [provided by RefSeq, alpha and beta, and other molecules containing terminal N-acetyl hexosamines, catalyzes the degradation of the ganglioside GM2, together with the cofactor GM2 activator protein, which are encoded by separate genes, Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHEXB chain A Conjugated
Short name Conjugated, HEXB chain A Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, HEXB epitope A (Antibody to)
Alternative techniqueantibodies
Identity 4879
Gene HEXB
Long gene name hexosaminidase subunit beta
Synonyms gene name hexosaminidase B (beta polypeptide)
Synonyms name beta-hexosaminidase subunit beta
Locus 5q13, 3
Discovery year 2001-06-22
GenBank acession M13519
Entrez gene record 3074
Pubmed identfication 2579389 3013851
RefSeq identity NM_000521
Havana BLAST/BLAT OTTHUMG00000102057
Locus Specific Databases HEXB Locus Database

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