Name : HEXDC Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN1549657089
| Long name | Biotin Conjugated, HEXDC Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HEXDC |
| Specificity | This is a highly specific antibody against HEXDC |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human HEXDC |
| Gene ID number | 284004 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome, Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides, N-acetyl-beta-galactosaminidase, The gene encoding HEXDC maps to human chromosome 17, Two key tumor suppressor genes are associated with chromosome 17, also known as hexosaminidase D, beta-hexosaminidase D, colon, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family, namely, p53 and BRCA1, prostate gland and fallopian tubes, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, HEXDC |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | FLJ23825 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HEXDC Conjugated |
| Short name | Conjugated, HEXDC Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, HEXDC (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26307 |
| Gene | HEXDC |
| Long gene name | hexosaminidase D |
| Synonyms gene name | catalytic domain) containing , hexosaminidase (glycosyl hydrolase family 20 |
| Synonyms name | cytosolic , hexosaminidase D |
| Locus | 17q25, 3 |
| Discovery year | 2006-01-12 |
| GenBank acession | AK074405 |
| Entrez gene record | 284004 |
| Pubmed identfication | 19040401 |
| RefSeq identity | NM_173620 |
| Havana BLAST/BLAT | OTTHUMG00000178836 |