Name : HEXDC Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4356850605
| Long name | FITC Conjugated, HEXDC Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HEXDC |
| Specificity | This is a highly specific antibody against HEXDC |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human HEXDC |
| Gene ID number | 284004 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | BRCA1 is directly involved in DNA repair and is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, Defects in p53 is associated with malignant cell growth and Li-Fraumeni syndrome, Existing as two alternatively spliced isoforms, HEXDC catalyzes the hydrolysis of non-reducing N-acetyl-D-hexosamine residues near the termini of N-acetyl-beta-D-hexosaminides, N-acetyl-beta-galactosaminidase, The gene encoding HEXDC maps to human chromosome 17, Two key tumor suppressor genes are associated with chromosome 17, also known as hexosaminidase D, beta-hexosaminidase D, colon, hexosaminidase domain-containing protein or beta-N-acetylhexosaminidase, is a 486 amino acid cytoplasmic and nuclear protein that has hexosaminidase activity and belongs to the glycosyl hydrolase 20 family, namely, p53 and BRCA1, prostate gland and fallopian tubes, which comprises over 2, 200 genes, 5% of the human genome and encodes over 1, HEXDC |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | FLJ23825 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HEXDC Conjugated |
| Short name | FITC Conjugated, HEXDC Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, HEXDC (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26307 |
| Gene | HEXDC |
| Long gene name | hexosaminidase D |
| Synonyms gene name | catalytic domain) containing , hexosaminidase (glycosyl hydrolase family 20 |
| Synonyms name | cytosolic , hexosaminidase D |
| Locus | 17q25, 3 |
| Discovery year | 2006-01-12 |
| GenBank acession | AK074405 |
| Entrez gene record | 284004 |
| Pubmed identfication | 19040401 |
| RefSeq identity | NM_173620 |
| Havana BLAST/BLAT | OTTHUMG00000178836 |