Name : hHBrk1 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5912794019
| Long name | ALEXA FLUOR 488 Conjugated, hHBrk1 Polyclonal Antibody |
| Also known as | Anti-hHBrk1 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | hHBrk1 |
| Specificity | This is a highly specific antibody against hHBrk1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human hHBrk1 |
| Gene ID Number | 55845 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex, Genetic depletion of HSPC300 results in cytoskeletal abnormalities and prevents cytokinesis of cells, HSPC300 is thought to be necessary for synaptic morphogenesis by motoneurons, HSPC300 is thought to localize to axons of the central nervous system of Drosophila embryos and thus may also be involved in axonogenesis, HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization, In Drosophila, In addition, In mice, The WAVE complex includes five proteins, and it is therefore hypothesized that HSPC300 may also be involved in cognitive functions, it is thought to have the same or similar functions in many different organisms, one of which is HSPC300, suggesting that decreased levels of HSPC300 may be associated with tumor suppression, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent, the WAVE/ARC pathway may affect the development of the nervous system, the knockout of the WAVE complex leads to learning and memory defects, HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | BRK1_HUMAN, C3ORF10 GENE, C3orf10 chromosome 3 open reading frame 10, Chromosome 3 open reading frame 10, HSPC300, MDS027, Probable protein BRICK1, hHBrk1, Brk1-like |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the hHBrk1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | hHBrk1 |
| Short name | hHBrk1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, hHBrk1 (Antibody to) |
| Alternative technique | antibodies |