Name : hHBrk1 Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN1418187620
| Long name | Cy5, 5 Conjugated, hHBrk1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | hHBrk1 |
| Specificity | This is a highly specific antibody against hHBrk1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human hHBrk1 |
| Gene ID number | 55845 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex, Genetic depletion of HSPC300 results in cytoskeletal abnormalities and prevents cytokinesis of cells, HSPC300 is thought to be necessary for synaptic morphogenesis by motoneurons, HSPC300 is thought to localize to axons of the central nervous system of Drosophila embryos and thus may also be involved in axonogenesis, HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization, In Drosophila, In addition, In mice, The WAVE complex includes five proteins, and it is therefore hypothesized that HSPC300 may also be involved in cognitive functions, it is thought to have the same or similar functions in many different organisms, one of which is HSPC300, suggesting that decreased levels of HSPC300 may be associated with tumor suppression, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent, the WAVE/ARC pathway may affect the development of the nervous system, the knockout of the WAVE complex leads to learning and memory defects, HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | BRK1_HUMAN, C3ORF10 GENE, C3orf10 chromosome 3 open reading frame 10, Chromosome 3 open reading frame 10, HSPC300, MDS027, Probable protein BRICK1, hHBrk1, Brk1-like |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | hHBrk1 Conjugated |
| Short name | Conjugated, hHBrk1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, hHBrk1 (Antibody to) |
| Alternative technique | antibodies |