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hHBrk1 Antibody, FITC Conjugated

hHBrk1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, hHBrk1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenhHBrk1
SpecificityThis is a highly specific antibody against hHBrk1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human hHBrk1
Gene ID number55845
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex, Genetic depletion of HSPC300 results in cytoskeletal abnormalities and prevents cytokinesis of cells, HSPC300 is thought to be necessary for synaptic morphogenesis by motoneurons, HSPC300 is thought to localize to axons of the central nervous system of Drosophila embryos and thus may also be involved in axonogenesis, HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization, In Drosophila, In addition, In mice, The WAVE complex includes five proteins, and it is therefore hypothesized that HSPC300 may also be involved in cognitive functions, it is thought to have the same or similar functions in many different organisms, one of which is HSPC300, suggesting that decreased levels of HSPC300 may be associated with tumor suppression, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent, the WAVE/ARC pathway may affect the development of the nervous system, the knockout of the WAVE complex leads to learning and memory defects, HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms BRK1_HUMAN, C3ORF10 GENE, C3orf10 chromosome 3 open reading frame 10, Chromosome 3 open reading frame 10, HSPC300, MDS027, Probable protein BRICK1, hHBrk1, Brk1-like
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targethHBrk1 Conjugated
Short name FITC Conjugated, hHBrk1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, hHBrk1 (Antibody to)
Alternative techniqueantibodies

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