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HIC2 Antibody

HIC2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHIC2 Primary Polyclonal Antibody
Also known asHIC2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHIC2
SpecificityThis is a highly specific antibody against HIC2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HIC2
Gene ID number23119
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen HIC-2 (hypermethylated in cancer 2) possesses zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, HIC-2 is also known as Hic-3, HIC-2 is highly expressed in cerebellum and is localized to the nucleus in cells, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, The majority of zinc-finger proteins contain a KrÃ, a transcriptional repressor, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing, as well as for the binding of transcription factors, most of which encompass some form of transcriptional activation or repression, suggesting that HIC-2 could possess tumor suppressor capabilities, thereby recruiting histone modifying proteins, which is thought to be important for protein-protein binding, which is thought to interact with KAP1, ¼, Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, ppel-type DNA binding domain and a KRAB domain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HIC2, HIC2_HUMAN, HRG22, Hic3, Hypermethylated in cancer 2 protein, KIAA1020, ZBTB30, ZNF907, Zinc finger and BTB domain-containing protein 30, HIC1 related gene on chromosome 22
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHIC2
Short nameHIC2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHIC2 (Antibody to)
Alternative techniqueantibodies
Identity 18595
Gene HIC2
Long gene name HIC ZBTB transcriptional repressor 2
Synonyms gene name hypermethylated in cancer 2
Synonyms KIAA1020 HRG22 ZBTB30 ZNF907
Locus 22q11, 21
Discovery year 2002-04-29
GenBank acession AB028943
Entrez gene record 23119
Pubmed identfication 11554746
Classification BTB domain containing Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000150781

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