HIC2 Antibody, Biotin Conjugated

HIC2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, HIC2 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	HIC2
Specificity	This is a highly specific antibody against HIC2
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human HIC2
Gene ID number	23119
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	HIC-2 (hypermethylated in cancer 2) possesses zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, HIC-2 is also known as Hic-3, HIC-2 is highly expressed in cerebellum and is localized to the nucleus in cells, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, The majority of zinc-finger proteins contain a KrÃ, a transcriptional repressor, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing, as well as for the binding of transcription factors, most of which encompass some form of transcriptional activation or repression, suggesting that HIC-2 could possess tumor suppressor capabilities, thereby recruiting histone modifying proteins, which is thought to be important for protein-protein binding, which is thought to interact with KAP1, ¼, Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, ppel-type DNA binding domain and a KRAB domain
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	KIAA1020 HRG22 ZBTB30 ZNF907
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	HIC2 Conjugated
Short name	Conjugated, HIC2 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, HIC2 (Antibody to)
Alternative technique	antibodies
Identity	18595
Gene	HIC2
Long gene name	HIC ZBTB transcriptional repressor 2
Synonyms gene name	hypermethylated in cancer 2
Locus	22q11, 21
Discovery year	2002-04-29
GenBank acession	AB028943
Entrez gene record	23119
Pubmed identfication	11554746
Classification	BTB domain containing Zinc fingers C2H2-type
Havana BLAST/BLAT	OTTHUMG00000150781

HIC2 Antibody, Biotin Conjugated

HIC2 Antibody, Biotin Conjugated size: 0.1ml 333

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