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HIF-1 Alpha Antibody, ALEXA FLUOR 647

HIF-1 Alpha Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, HIF-1 Alpha Polyclonal Antibody
Also known asAnti-HIF-1 Alpha PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHIF-1 Alpha
SpecificityThis is a highly specific antibody against HIF-1 Alpha
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range351-400/826
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human of human HIF-1 Alpha
Gene ID Number3091
Swiss ProtQ16665
Tested applications IF(ICC), IF(IHC-P)
Recommended dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Activation requires recruitment of transcriptional coactivators such as CREBPB and EP3, Activity is enhanced by interaction with both, Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters, HILPDA, Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP, Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia, NCOA1 or NCOA2, Plays an essential role in embryonic vascularization, Under hypoxic conditions, activates the transcription of over 4 genes, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia, glucose transporters, glycolytic enzymes, including erythropoietin, tumor angiogenesis and pathophysiology of ischemic disease, vascular endothelial growth factor, Functions as a master transcriptional regulator of the adaptive response to hypoxia
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms HYPB HIF-1 KIAA1732 FLJ23184 KMT3A
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the HIF-1 Alpha Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Description is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The HIF-1 Alpha Antibody
Gene targetHIF-1 Alpha
Short nameHIF-1 Alpha Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, HIF-1 a (Antibody to)
Alternative techniqueantibodies
Identity 18420
Gene SETD2
Long gene name SET domain containing 2
Locus 3p21, 31
Discovery year 2006-02-15
GenBank acession AJ238403
Entrez gene record 29072
Pubmed identfication 16118227 11461154
RefSeq identity NM_014159
Classification Lysine methyltransferases
Havana BLAST/BLAT OTTHUMG00000133514
Locus Specific Databases LRG_775

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