HIF-1 Alpha Antibody, Biotin Conjugated

HIF-1 Alpha Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, HIF-1 Alpha Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	HIF-1 Alpha
Specificity	This is a highly specific antibody against HIF-1 Alpha
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	351-400/826
Subcellular location	Nucleus, Cytoplasm
Source	KLH conjugated synthetic peptide derived from human of human HIF-1 Alpha
Gene ID number	3091
Swiss Prot	Q16665
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Activation requires recruitment of transcriptional coactivators such as CREBPB and EP3, Activity is enhanced by interaction with both, Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters, HILPDA, Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP, Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia, NCOA1 or NCOA2, Plays an essential role in embryonic vascularization, Under hypoxic conditions, activates the transcription of over 4 genes, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia, glucose transporters, glycolytic enzymes, including erythropoietin, tumor angiogenesis and pathophysiology of ischemic disease, vascular endothelial growth factor, Functions as a master transcriptional regulator of the adaptive response to hypoxia
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	HYPB HIF-1 KIAA1732 FLJ23184 KMT3A
Description	Conjugated is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The HIF-1 Alpha Antibody
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	HIF-1 Alpha Conjugated
Short name	Conjugated, HIF-1 Alpha Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, HIF-1 a (Antibody to)
Alternative technique	antibodies
Identity	18420
Gene	SETD2
Long gene name	SET domain containing 2
Locus	3p21, 31
Discovery year	2006-02-15
GenBank acession	AJ238403
Entrez gene record	29072
Pubmed identfication	16118227 11461154
RefSeq identity	NM_014159
Classification	Lysine methyltransferases
Havana BLAST/BLAT	OTTHUMG00000133514
Locus Specific Databases	LRG_775

HIF-1 Alpha Antibody, Biotin Conjugated

HIF-1 Alpha Antibody, Biotin Conjugated size: 0.1ml 333

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