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HIF-1 Alpha Antibody, Cy5.5 Conjugated

HIF-1 Alpha Antibody, Cy5.5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5, 5 Conjugated, HIF-1 Alpha Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation Cy5, 5, 5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHIF-1 Alpha
SpecificityThis is a highly specific antibody against HIF-1 Alpha
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range351-400/826
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human of human HIF-1 Alpha
Gene ID number3091
Swiss ProtQ16665
Tested applications IF(ICC), IF(IHC-P)
Recommended dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activation requires recruitment of transcriptional coactivators such as CREBPB and EP3, Activity is enhanced by interaction with both, Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters, HILPDA, Interaction with redox regulatory protein APEX seems to activate CTAD and potentiates activation by NCOA1 and CREBBP, Involved in the axonal distribution and transport of mitochondria in neurons during hypoxia, NCOA1 or NCOA2, Plays an essential role in embryonic vascularization, Under hypoxic conditions, activates the transcription of over 4 genes, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia, glucose transporters, glycolytic enzymes, including erythropoietin, tumor angiogenesis and pathophysiology of ischemic disease, vascular endothelial growth factor, Functions as a master transcriptional regulator of the adaptive response to hypoxia
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission675nm/694nm
Synonyms HYPB HIF-1 KIAA1732 FLJ23184 KMT3A
Description Conjugated is a &alpha, - or alpha protein sometimes glycoprotein present in blood, The HIF-1 Alpha Antibody
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths
Gene targetHIF-1 Alpha Conjugated
Short name Conjugated, HIF-1 Alpha Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label5, Cy5
Alternative name cyanine 5, 5 coupled, HIF-1 a (Antibody to)
Alternative techniqueantibodies
Identity 18420
Gene SETD2
Long gene name SET domain containing 2
Locus 3p21, 31
Discovery year 2006-02-15
GenBank acession AJ238403
Entrez gene record 29072
Pubmed identfication 16118227 11461154
RefSeq identity NM_014159
Classification Lysine methyltransferases
Havana BLAST/BLAT OTTHUMG00000133514
Locus Specific Databases LRG_775

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