Name : HIF-2-alpha Antibody
Supplier : NJS POLY
Price :389
SKU : GEN8820738056
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | HIF-2-alpha |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Rat |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Titration of the HIF-2-alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This HIF-2-alpha antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q9JHS1 |
| Purity | Antigen affinity |
| Description | HIF-2-alpha is predominantly expressed in highly vascularized tissues of adult humans and in endothelial cells of the mouse adult and embryo and may represent an important regulator of vascularization, The human EPAS1 gene contains 15 exons and spans at least 120 kb, The positions of the introns within the genomic region encoding the N-terminal bHLH-PAS domains of EPAS1 and AHR are similar, perhaps involving the regulation of endothelial cell gene expression in response to hypoxia, suggesting that the 5-prime ends of the two genes may have arisen from a gene duplication event, HIF-2-alpha is the protein product of the gene EPAS1 |
| Immunogen | Amino acids 202-240 (YNNCPPHSSLCGYKEPLLSCLIIMCEPIQHPSHMDIPLD-rat) were used as the immunogen for this HIF-2-alpha antibody |
| Storage | After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, The lyophilized HIF-2-alpha antibody can be stored at 4oC to -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | HIF-2-alpha |
| Short name | HIF-2-alpha Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | HIF-2-a (Antibody to) |
| Alternative technique | antibodies |