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HIF3 alpha Antibody, ALEXA FLUOR 594

HIF3 alpha Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, HIF3 alpha Polyclonal Antibody
Also known asAnti-H3 alpha PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenH3 alpha
SpecificityThis is a highly specific antibody against H3 alpha
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range161-200/669
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HIF3 alpha
Gene ID Number64344
Swiss ProtQ9Y2N7
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters, Conversely, Functions as an inhibitor of angiogenesis in the cornea (By similarity), Hypoxia induces down-regulation of isoform 4, Isoform 4 attenuates the binding of HIF1A to hypoxia-responsive elements (HRE), Isoform 4 has a dominant-negative function of inactivating HIF1A-mediated transcription, Isoform 4 may be a negative regulator of hypoxia-inducible gene expression in the kidney and may be involved in renal tumorigenesis, Suppresses hypoxia-inducible expression of HIF1A and EPAS1, The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE, leading to activation of HIF1A in hypoxia, the expression of isoform 4 increases and thereby secure an inhibition of HIF1A activity, thus inhibiting HRE-driven transcription, upon restoring normoxia, Involved in adaptive response to hypoxia
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms Basic-helix-loop-helix-PAS protein MOP7, Class E basic helix-loop-helix protein 17, HIF-3-alpha, HIF-3A, HIF3-alpha, HIF3-alpha-1, HIF3A, Hypoxia-inducible factor 3-alpha, Inhibitory PAS domain protein, MOP7, Member of PAS protein 7, PAS domain-containing protein 7, PASD7, bHLHe17, IPAS
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetHIF3 alpha
Short nameHIF3 alpha Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, HIF3 a (Antibody to)
Alternative techniqueantibodies

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