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HIP Antibody HSC70 Interacting Protein

HIP Antibody HSC70 Interacting Protein size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenHIP HSC70 Interacting Protein
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the HIP antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis HIP antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P50502
PurityAntigen affinity
Description HIP stabilized the ADP-bound form of Hsc70, Hohfeld et al, Hohfeld et al, One oligomer bound the ATPase domains of at least two Hsc70 molecules, ST13 is an abundant, They noted that colorectal, Using a yeast 2-hybrid assay, Zhang et al, also known as p48 or HIP, and binding was dependent on activation of the Hsc70 ATPase by Hsp40(DNAJB1), and ovarian carcinomas frequently show loss of heterozygosity at this site, breast, but is absent from the mature receptor complex, highly conserved protein that binds the major cytosolic chaperones heat-shock protein 70-kD (HSP70) and HSP90 during an intermediate stage of steroid receptor assembly, is a protein that in humans is encoded by the ST13 gene, which had a high affinity for a test protein substrate, (1995) concluded that the protein contributes to interactions of HSC70 with target proteins through its own chaperone activity, (1995) showed that rat HIP bound Hsc70(HSPA8), (1998) mapped the gene to chromosome 22q13 by fluorescence in situ hybridization, Suppression of Tumorigenicity 13
ImmunogenAn amino acid sequence from the N-terminus of human HSC70 Interacting Protein (MDPRKVNELRAFVKMCKQD) was used as the immunogen for this HIP antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HIP antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetHIP HSC70 Interacting Protein
Short nameHIP Antibody HSC70 Interacting Protein
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHIP (Antibody to) HSC70 Interacting Protein
Alternative techniqueantibodies
Identity 14866
Gene HHIP
Long gene name hedgehog interacting protein
Synonyms gene name hedgehog-interacting protein
Synonyms HIP FLJ20992
Locus 4q31, 21
Discovery year 2002-02-15
GenBank acession AK024645
Entrez gene record 64399
Pubmed identfication 11435703 11731473
Havana BLAST/BLAT OTTHUMG00000161428

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