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HIP2 Antibody

HIP2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHIP2 Primary Polyclonal Antibody
Also known asHIP2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHIP2
SpecificityThis is a highly specific antibody against HIP2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range69-93/200
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HIP2
Gene ID number3093
Swiss ProtP61086
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein, In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol, In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1, In vitro, May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53, Mediates the selective degradation of short-lived and abnormal proteins, Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B, Ubiquitinates huntingtin, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, in vitro supports ubiquitination of NFKB1, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins, Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names E2-25K, HIP-2, HIP2, HYPG, Huntingtin-interacting protein 2, UBC1, UBE2K, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2 K, Ubiquitin-conjugating enzyme E2(25K), Ubiquitin-conjugating enzyme E2-25 kDa, Ubiquitin-conjugating enzyme E2-25K, Ubiquitin-protein ligase, LIG
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHIP2
Short nameHIP2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHIP2 (Antibody to)
Alternative techniqueantibodies
Identity 4914
Gene UBE2K
Long gene name ubiquitin conjugating enzyme E2 K
Synonyms gene HIP2
Synonyms gene name huntingtin interacting protein 2 ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) ubiquitin-conjugating enzyme E2K
Synonyms HYPG UBC1
Locus 4p14
Discovery year 1997-08-28
GenBank acession U58522
Entrez gene record 3093
Pubmed identfication 8702625 17873885
RefSeq identity NM_005339
Classification Ubiquitin conjugating enzymes E2
Havana BLAST/BLAT OTTHUMG00000160543

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