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HIPPI Antibody, Biotin Conjugated

HIPPI Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, HIPPI Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHIPPI
SpecificityThis is a highly specific antibody against HIPPI
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human HIPPI
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Huntingtonâ, Polyglutamine expansion reduces the level of association between Hip-1 and Htt, The Hippi-Hip-1 heterodimer is a pro-apoptotic complex that recruits procaspase-8 and initiates caspase-8 activation, The human hippi gene maps to chromosome 3q13, thereby increasing levels of free Hip-1 that then can be the candidate protein Hippi (Hip-1 protein interactor), which may contribute to the neuronal cell death observed in individuals diagnosed with Huntingtonâ, which occur later in human life, &euro, &euro, &trade, &trade, 13 and encodes a 429 amino acid protein, Programmed neuronal cell death is a feature of neurodegenerative disorders such as Alzheimer's and Huntington's disease, s disease, s disease at the molecular and cell level is characterized by polyglutamine expansion of the protein huntingtin (Htt) that leads to apoptotis-mediated neurodegenerative loss of medium spiny neurons throughout the striatum
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FLJ10147 HIPPI MHS4R2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHIPPI Conjugated
Short name Conjugated, HIPPI Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, HIPPI (Antibody to)
Alternative techniqueantibodies
Identity 17367
Gene IFT57
Long gene name intraflagellar transport 57
Synonyms gene ESRRBL1
Synonyms gene name estrogen-related receptor beta like 1 intraflagellar transport 57 homolog (Chlamydomonas)
Locus 3q13, 12-q13, 13
Discovery year 2002-01-18
GenBank acession AK001009
Entrez gene record 55081
RefSeq identity NM_018010
Classification Intraflagellar transport proteins
Havana BLAST/BLAT OTTHUMG00000159223

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