Name : HIPPI Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN6557590338
| Long name | Cy3 Conjugated, HIPPI Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HIPPI |
| Specificity | This is a highly specific antibody against HIPPI |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human HIPPI |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Huntingtonâ, Polyglutamine expansion reduces the level of association between Hip-1 and Htt, The Hippi-Hip-1 heterodimer is a pro-apoptotic complex that recruits procaspase-8 and initiates caspase-8 activation, The human hippi gene maps to chromosome 3q13, thereby increasing levels of free Hip-1 that then can be the candidate protein Hippi (Hip-1 protein interactor), which may contribute to the neuronal cell death observed in individuals diagnosed with Huntingtonâ, which occur later in human life, &euro, &euro, &trade, &trade, 13 and encodes a 429 amino acid protein, Programmed neuronal cell death is a feature of neurodegenerative disorders such as Alzheimer's and Huntington's disease, s disease, s disease at the molecular and cell level is characterized by polyglutamine expansion of the protein huntingtin (Htt) that leads to apoptotis-mediated neurodegenerative loss of medium spiny neurons throughout the striatum |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | FLJ10147 HIPPI MHS4R2 |
| Properties | 1 of the HIPPI Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HIPPI Conjugated |
| Short name | Conjugated, HIPPI Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, HIPPI (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17367 |
| Gene | IFT57 |
| Long gene name | intraflagellar transport 57 |
| Synonyms gene | ESRRBL1 |
| Synonyms gene name | estrogen-related receptor beta like 1 intraflagellar transport 57 homolog (Chlamydomonas) |
| Locus | 3q13, 12-q13, 13 |
| Discovery year | 2002-01-18 |
| GenBank acession | AK001009 |
| Entrez gene record | 55081 |
| RefSeq identity | NM_018010 |
| Classification | Intraflagellar transport proteins |
| Havana BLAST/BLAT | OTTHUMG00000159223 |