Name : Hippocalcin Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8395791587
| Long name | Hippocalcin Primary Polyclonal Antibody |
| Also known as | Hippocalcin PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Hippocalcin |
| Specificity | This is a highly specific antibody against Hippocalcin |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hippocalcin |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In order to regulate kinase and phospholipase activity, The hippocalcin protein is highly conserved in mouse, The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation, Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging, with increased expression observed in hippocampal pyramidal cells, Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BDR2, Calcium binding protein BDR 2, Calcium binding protein BDR2, Calcium-binding protein BDR-2, HPCA_HUMAN, Hpca, Neuron specic calcium binding protein hippocalcin, Neuron specic calcium-binding protein hippocalcin, Neuron-specic calcium-binding protein hippocalcin, BDR 2, P23K |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Hippocalcin |
| Short name | Hippocalcin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Hippocalcin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 5144 |
| Gene | HPCA |
| Long gene name | hippocalcin |
| Locus | 1p35, 1 |
| Discovery year | 1994-12-14 |
| GenBank acession | BC001777 |
| Entrez gene record | 3208 |
| Pubmed identfication | 8166736 9931466 |
| RefSeq identity | NM_002143 |
| Classification | EF-hand domain containing |
| Havana BLAST/BLAT | OTTHUMG00000004017 |