Name : Histone H1.4(Thr18) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN6836753470
| Long name | 4(Thr18) Primary Polyclonal Antibody, Histone H1 |
| Also known as | 4(Thr18) PAb, Histone H1 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | 4 Thr18, Histone H1 |
| Specificity | Due to the highly conserved nature of these histones, This phosphorylation site is found in Rat H1C as well, This phosphorylation site is homologous to Thr18 in Rat H1C/H1D and Mouse H1D, but not Human or Mouse H1C, this antibody may react with these members when phosphorylated at this site, 4 Thr18, This is a highly specific antibody against Histone H1 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Thr18 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 2-30/219 |
| Subcellular location | Nucleus |
| Source | 4 around the phosphorylation site of Thr18, KLH conjugated synthetic phosphopeptide derived from human Histone H1 |
| Gene ID number | 3008 |
| Swiss Prot | P10412 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts also as a regulator of individual gene transcription through chromatin remodeling, Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers, nucleosome spacing and DNA methylation (By similarity), Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | H1, H1F4, H1s-4, HIST1H1E, Histone H1, Histone H1b, Histone H1s-4, dJ221C16, 4, 4, 5, H1E |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | 4(Thr18), Histone H1 |
| Short name | 4(Thr18) Antibody, Histone H1 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 4(Thr18) (Antibody to), Histone H1 |
| Alternative technique | antibodies |
| Identity | 4718 |
| Gene | HIST1H1E |
| Long gene name | histone cluster 1 H1 family member e |
| Synonyms gene | H1F4 |
| Synonyms gene name | H1 histone family, H1e , H1e histone cluster 1, member 4 histone 1 |
| Synonyms | H1, 4 H1e H1s-4 |
| Locus | 6p22, 2 |
| Discovery year | 1988-08-31 |
| GenBank acession | M60748 |
| Entrez gene record | 3008 |
| Pubmed identfication | 1916825 12408966 |
| RefSeq identity | NM_005321 |
| Classification | Histones |
| Havana BLAST/BLAT | OTTHUMG00000014422 |