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Histone H2A.X (Ser140) Antibody

Histone H2A.X (Ser140) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHistone H2A, X (Ser140) Antibody
Also known asHistone H2A, X (Ser140) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHistone H2A, X Ser140
Specificity This phosphorylation site is homologous to that of Ser140 in Mouse and Rat, This is a highly specific antibody against Histone H2A, X Ser140
Modification(s)Phosphorylation
Modification site(s)Ser140
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range100-142/143
Subcellular locationNucleus
SourceKLH conjugated synthetic phosphopeptide derived from human Histone H2AX around the phosphorylation site of Ser140
Gene ID number3014
Swiss ProtP16104
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen DNA accessibility is regulated via a complex set of post-translational modifications of histones, DNA repair, DNA replication and chromosomal stability, Histones thereby play a central role in transcription regulation, Nucleosomes wrap and compact DNA into chromatin, Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation, also called histone code, and nucleosome remodeling, limiting DNA accessibility to the cellular machineries which require DNA as a template, Variant histone H2A which replaces conventional H2A in a subset of nucleosomes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names H2A, H2A/X, H2AFX, Histone H2A, Histone H2AX, H2AX, X, X
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHistone H2A, X (Ser140)
Short nameHistone H2A, X (Ser140) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHistone H2A, X (Ser140) (Antibody to)
Alternative techniqueantibodies

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