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Histone H2A.X (Ubiquityl Lys119) Antibody, Biotin Conjugated

Histone H2A.X (Ubiquityl Lys119) Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, Histone H2A, X (Ubiquityl Lys119) Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHistone H2A, X Ubiquityl Lys119
Specificity This modification site is homologous to that of Lys119 in Rat, This is a highly specific antibody against Histone H2A, X Ubiquityl Lys119
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range90-130/143
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human Ubiquityl Histone H2A, X (Lys119)
Gene ID number3014
Swiss ProtP16104
Tested applicationsIHC-P
Recommended dilutionsIHC-P(1:100-500)
Crossreactivity Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background DNA accessibility is regulated via a complex set of post-translational modifications of histones, DNA repair, DNA replication and chromosomal stability, Histones thereby play a central role in transcription regulation, Nucleosomes wrap and compact DNA into chromatin, Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation, also called histone code, and nucleosome remodeling, limiting DNA accessibility to the cellular machineries which require DNA as a template, Variant histone H2A which replaces conventional H2A in a subset of nucleosomes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms H2A, H2A/X, H2AFX, Histone H2A, Histone H2AX, H2AX, X, X
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHistone H2A, X (Ubiquityl Lys119) Conjugated
Short name Conjugated, Histone H2A, X (Ubiquityl Lys119) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Histone H2A, X (Ubiquityl Lys119) (Antibody to)
Alternative techniqueantibodies

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