Name : Histone H3 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5770125774
| Long name | ALEXA FLUOR 594 Conjugated, Histone H3 Polyclonal Antibody |
| Also known as | Anti-Histone H3 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Histone H3 |
| Specificity | This is a highly specific antibody against Histone H3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 90-136/136 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Histone H3 |
| Gene ID Number | 3020 |
| Swiss Prot | P84243 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Pig, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis, DNA accessibility is regulated via a complex set of post-translational modifications of histones, DNA repair, DNA replication and chromosomal stability, Deposited at sites of nucleosomal displacement throughout transcribed genes, Histones thereby play a central role in transcription regulation, Nucleosomes wrap and compact DNA into chromatin, also called histone code, and nucleosome remodeling, limiting DNA accessibility to the cellular machineries which require DNA as a template, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin, Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | H3t H3/g H3, 4 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | Histone H3 |
| Short name | Histone H3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, Histone H3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4778 |
| Gene | HIST3H3 |
| Long gene name | histone cluster 3 H3 |
| Synonyms gene | H3FT |
| Synonyms gene name | H3 , H3 histone cluster 3, H3 histone family, member T histone 3 |
| Locus | 1q42, 13 |
| Discovery year | 1998-09-30 |
| GenBank acession | Z49861 |
| Entrez gene record | 8290 |
| Pubmed identfication | 8834248 12408966 |
| RefSeq identity | NM_003493 |
| Classification | Histones |
| Havana BLAST/BLAT | OTTHUMG00000040044 |