Name : HK2/Hexokinase 2 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN7130874302
| Long name | Cy3 Conjugated, HK2/Hexokinase 2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | HK2/Hexokinase 2 |
| Specificity | This is a highly specific antibody against HK2/Hexokinase 2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human Hexokinase 2 |
| Gene ID number | 3099 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Four hexokinase isoenzymes have been identified, Glucokinase is expressed in pancreatic beta cells where it functions as a glucose sensor, Glucokinase lacks the N-terminal hydrophobic cluster, HXK I has been shown to be expressed in brain, HXK II is involved in the uptake and utilization of glucose by adipose and skeletal tissues, HXK III has the highest affinity for glucose, Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids, Of the hexokinases, The hydrophobic cluster is thought to be necessary for membrane binding, This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases, also designated glucokinase or GCK), determining the â, hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, including hexokinase I (HXK I), kidney and heart tissues as well as in hepatoma cell lines, the conversion of glucose to glucose-6-phosphate, &euro, &euro, &oelig, The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, set pointâ, for insulin secretion |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Properties | 1 of the HK2/Hexokinase 2 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HK2/Hexokinase 2 Conjugated |
| Short name | Conjugated, HK2/Hexokinase 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, HK2/Hexokinase 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4923 |
| Gene | HK2 |
| Long gene name | hexokinase 2 |
| Locus | 2p12 |
| Discovery year | 1993-03-11 |
| Entrez gene record | 3099 |
| RefSeq identity | NM_000189 |
| Havana BLAST/BLAT | OTTHUMG00000129972 |