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HLA-A Antibody

HLA-A Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenHLA-A
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the HLA-A antibody should be determined by the researcher
Intented useThis HLA-A antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P01892
PurityAntigen affinity
Description And it is critical to the cytotoxic t-cell controlled immune response to viruses and other intracellular pathogens, Because each HLA-A gene has a high affinity for slightly different peptides, For similar reasons, HLA is simply the major histocompatibility complex (MHC) specific to humans, HLA-A is one of three major types of human MHC class I cell surface receptors, HLA-A matching is essential to successful tissue transplants, The others are HLA-B and HLA-C, and/or increased severity of many diseases, certain HLA-As are associated with increased risk, is a group of human leukocyte antigens (HLA) that are coded for by the HLA-A locus, more rapid progression, namely HLA A, which is located at human chromosome 6p21, 3, HLA-A
ImmunogenAmino acids EYWDGETRKVKAHSQTHRVDLGTLR of human HLA-A were used as the immunogen for the HLA-A antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HLA-A antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetHLA-A
Short nameHLA-A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name A (Antibody to), class I, major histocompatibility complex
Alternative techniqueantibodies
Alternative to gene target A, Cell surfaces, HLA-A and IDBG-298637 and ENSG00000206503 and 3105, HLAA, TAP binding, TAP-dependent and biological process this GO :0002480 and antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent and biological process this GO :0005515 and protein binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009986 and cell surface and cellular component this GO :0012507 and ER to this GO lgi transport vesicle membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019882 and antigen processing and presentation and biological process this GO :0030670 and pha this GO cytic vesicle membrane and cellular component this GO :0030881 and beta-2-microglobulin binding and molecular function this GO :0031901 and early endosome membrane and cellular component this GO :0042270 and protection from natural killer cell mediated cytotoxicity and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042605 and peptide antigen binding and molecular function this GO :0042612 and MHC class I protein complex and cellular component this GO :0046977 and TAP binding and molecular function this GO :0050776 and regulation of immune response and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071556 and integral component of lumenal side of endoplasmic reticulum membrane and cellular component, class I, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001916 and positive regulation of T cell mediated cytotoxicity and biological process this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0030881: beta-2-microglobulin binding and also this GO :0042605: peptide antigen binding and also this GO :0046977: TAP binding, this GO :0030881: beta-2-microglobulin binding, this GO :0042605: peptide antigen binding, this GO :0046977: TAP binding, major histocompatibility complex
Identity 4931
Gene HLA-A
Long gene name A , class I, major histocompatibility complex
Locus 6p22, 1
Discovery year 2001-06-22
GenBank acession D32129
Entrez gene record 3105
Pubmed identfication 8838351
RefSeq identity NM_002116
Classification C1-set domain containing Histocompatibility complex
Havana BLAST/BLAT OTTHUMG00000130501
Locus Specific Databases IMGT/HLA Database

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