Filters

HLA-B (528CT10.4.1) Monoclonal Antibody

HLA-B (528CT10.4.1) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name1) Monoclonal Antibody, 4, HLA-B (528CT10
Also known as1) Monoclonal Antibody, 4, HLA-B (528CT10
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHLA-B
SpecificityThis is a highly specific antibody against HLA-B
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1, 4, 528CT10
SourceThis HLA-B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from human HLA-B
Swiss ProtP03989
Tested ApplicationsWB
Recommended dilutionsWB(1:100~250)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen, Exon 1 encodes the leader peptide, Hundreds of HLA-B alleles have been described, Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule, The heavy chain is anchored in the membrane, The heavy chain is approximately 45 kDa and its gene contains 8 exons, They are expressed in nearly all cells, This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin), Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation, exon 2 and 3 encode the alpha1 and alpha2 domains, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail, which both bind the peptide, HLA-B belongs to the HLA class I heavy chain paralogues
Purification method This antibody is prepared by Euglobin precipitation followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target1) Monoclonal, 4, HLA-B (528CT10
Short name1) Monoclonal Antibody, 4, HLA-B (528CT10
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name B (528CT10, class I, 1) monoclonal (Antibody to), 4, major histocompatibility complex
Alternative techniqueantibodies
Alternative to gene target AS and HLAB and SPDA1, B, Cell surfaces, HLA-B and IDBG-299578 and ENSG00000234745 and 3106, TAP-dependent and biological process this GO :0002480 and antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent and biological process this GO :0002667 and regulation of T cell anergy and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0009986 and cell surface and cellular component this GO :0012507 and ER to this GO lgi transport vesicle membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019882 and antigen processing and presentation and biological process this GO :0030670 and pha this GO cytic vesicle membrane and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0032655 and regulation of interleukin-12 production and biological process this GO :0032675 and regulation of interleukin-6 production and biological process this GO :0042270 and protection from natural killer cell mediated cytotoxicity and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042605 and peptide antigen binding and molecular function this GO :0042612 and MHC class I protein complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0050776 and regulation of immune response and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071556 and integral component of lumenal side of endoplasmic reticulum membrane and cellular component this GO :2001198 and regulation of dendritic cell differentiation and biological process, class I, peptide antigen binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001916 and positive regulation of T cell mediated cytotoxicity and biological process this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0042605: peptide antigen binding, this GO :0005515: protein binding, this GO :0042605: peptide antigen binding, major histocompatibility complex
Identity 4932
Gene HLA-B
Long gene name B , class I, major histocompatibility complex
Synonyms gene AS
Synonyms gene name ankylosing spondylitis
Locus 6p21, 33
Discovery year 2001-06-22
GenBank acession M15470
Entrez gene record 3106
Pubmed identfication 3459708
RefSeq identity NM_005514
Classification C1-set domain containing Histocompatibility complex
Havana BLAST/BLAT OTTHUMG00000031153
Locus Specific Databases IMGT/HLA Database

Similar products

Subscribe to our Newsletter