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HMBS Antibody, FITC Conjugated

HMBS Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, HMBS Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHMBS
SpecificityThis is a highly specific antibody against HMBS
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human HMBS/PBGD
Gene ID number3145
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background AIP is characterized by acute attacks of neurological dysfunctions with hypertension, Deficiency of PBGD causes errors in pyrrole metabolism, PBGD belongs to the HMBS (hydroxymethylbilane synthase) family, abdominal pain and excessive amounts of aminolevulinic acid and porphobilinogen in the urine, also designated hydroxymethylbilane synthase, is a cytoplasmic enzyme found in the heme synthesis pathway, peripheral neurologic disturbances, tachycardia, which in turn leads to an inherited autosomal disorder called acute intermittent porphyria (AIP), PBGD
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHMBS Conjugated
Short name FITC Conjugated, HMBS Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, HMBS (Antibody to)
Alternative techniqueantibodies
Identity 4982
Gene HMBS
Long gene name hydroxymethylbilane synthase
Synonyms gene PBGD UPS PORC
Synonyms gene name Chester type , acute, uroporphyrinogen I synthase porphobilinogen deaminase porphyria
Locus 11q23, 3
Discovery year 1986-01-01
GenBank acession X04808
Entrez gene record 3145
Pubmed identfication 8432552 17298217
RefSeq identity NM_000190
Havana BLAST/BLAT OTTHUMG00000168295
Locus Specific Databases LRG_1076

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