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HMGB2 Antibody

HMGB2 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenHMGB2
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the HMGB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis HMGB2 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P26583
PurityPurified
Description In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles, The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells, These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility, This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination, HMGB2 is a member of the non-histone chromosomal high mobility group protein family
ImmunogenA portion of amino acids 92-118 from the human protein was used as the immunogen for this HMGB2 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the HMGB2 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetHMGB2
Short nameHMGB2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namehigh mobility family box 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA binding, DNA ligation and biological process this GO :0006309 and apoptotic DNA fragmentation and biological process this GO :0006325 and chromatin organization and biological process this GO :0006334 and nucleosome assembly and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007289 and spermatid nucleus differentiation and biological process this GO :0008301 and DNA binding, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048545 and response to steroid hormone and biological process this GO :0050786 and RAGE receptor binding and molecular function this GO :0050918 and positive chemotaxis and biological process this GO :0051103 and DNA ligation involved in DNA repair and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process, HMG2, HMGB2 and IDBG-44657 and ENSG00000164104 and 3148, HMGB2 and IDBG-629304 and ENSBTAG00000015101 and 540444, Hmgb2 and IDBG-156235 and ENSMUSG00000054717 and 97165, bending, bending and also this GO :0019904: protein domain specific binding and also this GO :0042056: chemoattractant activity and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0044822: poly(A) RNA binding and also this GO :0050786: RAGE receptor binding, bending and molecular function this GO :0008584 and male this GO nad development and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0032075 and positive regulation of nuclease activity and biological process this GO :0033151 and V(D)J recombination and biological process this GO :0042056 and chemoattractant activity and molecular function this GO :0043234 and protein complex and cellular component this GO :0043388 and positive regulation of DNA binding and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045648 and positive regulation of erythrocyte differentiation and biological process this GO :0045654 and positive regulation of megakaryocyte differentiation and biological process this GO :0045892 and negative regulation of transcription, nuclei, this GO :0000793 and condensed chromosome and cellular component this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003697 and single-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006265 and DNA topological change and biological process this GO :0006288 and base-excision repair, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003684: damaged DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003697: single-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008301: DNA binding, this GO :0003684: damaged DNA binding, this GO :0003690: double-stranded DNA binding, this GO :0003697: single-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008301: DNA binding, this GO :0019904: protein domain specific binding, this GO :0042056: chemoattractant activity, this GO :0044212: transcription regulatory region DNA binding, this GO :0044822: poly(A) RNA binding, this GO :0050786: RAGE receptor binding, 618297, high mobility group box 2
Identity 5000
Gene HMGB2
Long gene name high mobility group box 2
Synonyms gene HMG2
Synonyms gene name high-mobility group (nonhistone chromosomal) protein 2 high-mobility group box 2
Locus 4q34, 1
Discovery year 1993-12-13
Entrez gene record 3148
Pubmed identfication 1754403
RefSeq identity NM_001130688
Classification Canonical high mobility group
Havana BLAST/BLAT OTTHUMG00000160799

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