Name : HMGCL Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4145368701
| Long name | HMGCL Primary Polyclonal Antibody |
| Also known as | HMGCL PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | HMGCL |
| Specificity | This is a highly specific antibody against HMGCL |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HMGCL |
| Gene ID number | 2835 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Defects in HMGCL are the cause of 3-hydroxy-3-methylglutaryl-CoA lyase deficiency (hydroxymethylglutaricaciduria), It has a role in ketogenesis and leucine catabolism, an autosomal recessive disease which can lead to hypoglycemia and coma, liver and lymphoblasts, Hydroxymethylglutaryl-CoA lyase (HMGCL) is found in fibroblasts |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 3 hydroxy 3 methylglutaryl Coenzyme A lyase, 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase, 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase hydroxymethylglutaricaciduria, 3-hydroxy-3-methylglutarate-CoA lyase, HL, HMG CoA Lyase Deficiency, HMG CoA lyase, HMG-CoA lyase, HMGCL, HMGCL_HUMAN, Hydroxymethylglutaricaciduria, Hydroxymethylglutaryl CoA lyase, Hydroxymethylglutaryl CoA lyase mitochondrial, Hydroxymethylglutaryl-CoA lyase, MS725, OTTHUMP00000044830, mitochondrial, 3 hydroxy 3 methylglutaryl CoA lyase |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HMGCL |
| Short name | HMGCL Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | HMGCL (Antibody to) |
| Alternative technique | antibodies |
| Identity | 5005 |
| Gene | HMGCL |
| Long gene name | 3-hydroxymethyl-3-methylglutaryl-CoA lyase |
| Synonyms gene name | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase |
| Synonyms | HL |
| Synonyms name | hydroxymethylglutaricaciduria |
| Locus | 1p36, 11 |
| Discovery year | 1993-12-13 |
| GenBank acession | BC010570 |
| Entrez gene record | 3155 |
| Pubmed identfication | 8102917 8978493 |
| RefSeq identity | NM_000191 |
| Havana BLAST/BLAT | OTTHUMG00000002963 |