Filters

HNF1 beta Antibody, Biotin Conjugated

HNF1 beta Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, HNF1 beta Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHNF1 beta
SpecificityThis is a highly specific antibody against HNF1 beta
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human HNF1 beta
Gene ID number6928
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Evidence suggests that HNF-6 may also be a transriptional activator for at least 22 other hepatocyte-enriched genes, HNF-3 (a, HNF-3a, HNF-3a and HNF-3b have also been shown to be involved in gastrulation events such as body axis formation, HNF-3b and HNF-3g regulate the transcription of numerous hepatocyte genes in adult liver, HNF-4 (a and g) and HNF-6 compose, HNF-4a and HNF-4g have been shown to be important for early embryo development, HNF-4a is expressed in liver, HNF-6 has been shown to bind to the promoter of HNF-3b, The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, a homoeprotein family designated the hepatocyte nuclear factor family, and HNF-4g is expressed in each of these tissues except liver, b and g), in part, including cytochrome P450 2C13 and a-1 antitrypsin, kidney, pancreas, small intestine, small intestine and thymus, testis and colon, which indicates a potential role of HNF-6 in gut endoderm epithelial cell differentiation, HNF-1 (a and b)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms HNF1 LFB1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetHNF1 beta Conjugated
Short name Conjugated, HNF1 beta Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, HNF1 b (Antibody to)
Alternative techniqueantibodies
Identity 11621
Gene HNF1A
Long gene name HNF1 homeobox A
Synonyms gene MODY3 TCF1
Synonyms gene name LF-B1, albumin proximal factor , hepatic, hepatic nuclear factor (HNF1), transcription factor 1
Locus 12q24, 31
Discovery year 1990-02-12
GenBank acession M57732
Entrez gene record 6927
Pubmed identfication 1535333 7795649
RefSeq identity NM_000545
Classification HNF class homeoboxes
Havana BLAST/BLAT OTTHUMG00000151015
Locus Specific Databases Monogenic Diabetes LRG_522

Subscribe to our Newsletter