Name : HNF1B Antibody
Supplier : NJS POLY
Price :199
SKU : GEN9447956131
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | HNF1B |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB |
| Recommended dilutions | Western blot: 1:1000 |
| Notes | Titration of the HNF1B antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This HNF1B antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P35680 |
| Purity | Antigen affinity |
| Description | Multiple transcript variants encoding different isoforms have been found for this gene, Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, The gene has been shown to function in nephron development, The protein binds to DNA as either a homodimer, and expression of this gene is altered in some types of cancer, and regulates development of the embryonic pancreas, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha, This gene encodes a member of the homeodomain-containing superfamily of transcription factors |
| Immunogen | A portion of amino acids 498-529 from the human protein was used as the immunogen for this HNF1B antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the HNF1B antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | HNF1B |
| Short name | HNF1B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | HNF1B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11630 |
| Gene | HNF1B |
| Long gene name | HNF1 homeobox B |
| Synonyms gene | TCF2 |
| Synonyms gene name | LF-B3, hepatic, transcription factor 2, variant hepatic nuclear factor |
| Synonyms | LFB3 VHNF1 HNF1beta MODY5 |
| Locus | 17q12 |
| Discovery year | 1990-05-28 |
| GenBank acession | BC017714 |
| Entrez gene record | 6928 |
| Pubmed identfication | 1677179 10484768 |
| RefSeq identity | NM_000458 |
| Classification | HNF class homeoboxes |
| Havana BLAST/BLAT | OTTHUMG00000188478 |