| Long name | Recombinant Horse Interleukin-1 receptor antagonist protein (IL1RN) |
| Alternative names | IL-1RN, IL1 inhibitor, IL1 inhibitor, IRAP, Interleukin-1 receptor antagonist protein, interleukin-1 receptor antagonist protein, interleukin-1 receptor antagonist secretory form, interleukin-1 receptor antagonist protein |
| Gene name | IL1RN |
| Other gene names | IL-1RA, IL-1RN, IL-1ra, IL1RA, IL1RN, IRAP, IL1RN |
| General description | All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Interleukin-1 receptor antagonist protein (IL1RN) is a recombinant protein expressed in Baculovirus |
| Product category | Recombinant Proteins |
| Expression system | Baculovirus |
| Available also expressed in: | Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity | Greater than 90% (determined by SDS-PAGE) |
| Form | Lyophilized protein |
| Storage | Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications | IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Description | 2 or 3 and , However, In this sense, MBS Recombinant Proteins produces more antagonist and receptor related products as 1, The receptors are ligand binding factors of type 1, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The antagonist receptor ligand binding will be in contrast with agonist activity, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Properties | A blocking solution for the native horse or equine immunoglobulins in available in the ELISA protocol, ELISA test are used to determine quantitatively the presence in horse serum of the antigen by a polyclonal antibody to the equine epitope selected for the ELISA kit, Immunoglobulins, (Equus ferus caballus) sera and plasma contain equine IgGs, Horse |
| Gene target | Interleukin-1 receptor antagonist protein (IL1RN) |
| Short name | Interleukin-1 receptor antagonist protein (IL1RN) |
| Host | Horse |
| Species | Horses, Horse |
| Alternative name | Horse Interleukin-1 receptor antagonist protein (interleukin 1 receptor anta this GO nist) |
| Alternative to gene target | DIRA and ICIL-1RA and IL-1ra and IL-1ra3 and IL-1RN and IL1F3 and IL1RA and IRAP and MVCD4, Extracellular, IL1RN and IDBG-634670 and ENSBTAG00000019665 and 281860, IL1RN and IDBG-66814 and ENSG00000136689 and 3557, Il1rn and IDBG-142372 and ENSMUSG00000026981 and 16181, Type I receptor binding, Type I receptor binding and also this GO :0005151: interleukin-1, Type I receptor binding and molecular function this GO :0005151 and interleukin-1, Type II receptor binding, Type II receptor binding and also this GO :0005152: interleukin-1 receptor anta this GO nist activity and also this GO :0045352: interleukin-1 Type I receptor anta this GO nist activity and also this GO :0045353: interleukin-1 Type II receptor anta this GO nist activity, Type II receptor binding and molecular function this GO :0005152 and interleukin-1 receptor anta this GO nist activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006953 and acute-phase response and biological process this GO :0006955 and immune response and biological process this GO :0007565 and female pregnancy and biological process this GO :0007613 and memory and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0014050 and negative regulation of glutamate secretion and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014823 and response to activity and biological process this GO :0019233 and sensory perception of pain and biological process this GO :0019752 and carboxylic acid metabolic process and biological process this GO :0030073 and insulin secretion and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0031982 and vesicle and cellular component this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034115 and negative regulation of heterotypic cell-cell adhesion and biological process this GO :0042493 and response to drug and biological process this GO :0042594 and response to starvation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0045352 and interleukin-1 Type I receptor anta this GO nist activity and molecular function this GO :0045353 and interleukin-1 Type II receptor anta this GO nist activity and molecular function this GO :0045837 and negative regulation of membrane potential and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070555 and response to interleukin-1 and biological process this GO :0070670 and response to interleukin-4 and biological process this GO :0071874 and cellular response to norepinephrine stimulus and biological process this GO :2000660 and negative regulation of interleukin-1-mediated signaling pathway and biological process, interleukin-1, this GO :0001660 and fever generation and biological process this GO :0001960 and negative regulation of cytokine-mediated signaling pathway and biological process this GO :0002439 and chronic inflammatory response to antigenic stimulus and biological process this GO :0005149 and interleukin-1 receptor binding and molecular function this GO :0005150 and interleukin-1, this GO :0005149: interleukin-1 receptor binding, this GO :0005149: interleukin-1 receptor binding and also this GO :0005150: interleukin-1, this GO :0005150: interleukin-1, this GO :0005151: interleukin-1, this GO :0005152: interleukin-1 receptor anta this GO nist activity, this GO :0045352: interleukin-1 Type I receptor anta this GO nist activity, this GO :0045353: interleukin-1 Type II receptor anta this GO nist activity, interleukin 1 receptor anta this GO nist |
| Identity | 6000 |
| Gene | IL1RN |
| Long gene name | interleukin 1 receptor antagonist |
| Synonyms | IL1RA ICIL-1RA IL1F3 IRAP IL-1RN MGC10430 |
| Synonyms name | interleukin-1 receptor antagonist protein intracellular interleukin-1 receptor antagonist |
| Locus | 2q14, 1 |
| Discovery year | 1990-11-20 |
| GenBank acession | M55646 |
| Entrez gene record | 3557 |
| Pubmed identfication | 1386337 8432529 |
| RefSeq identity | NM_173841 |
| Classification | Endogenous ligands Interleukins Interleukin receptors |
| Havana BLAST/BLAT | OTTHUMG00000131341 |
| Locus Specific Databases | LRG_188 |
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