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HOXD9 Antibody

HOXD9 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHOXD9 Primary Polyclonal Antibody
Also known asHOXD9 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHOXD9
SpecificityThis is a highly specific antibody against HOXD9
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HOXD9
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activation of HoxD9 depends on the structure of the target regulatory element, Furthermore, HoxD9 may be a multifunctional transcriptional regulator, HoxD9 transcripts are also detected in the synovial tissue of arthritic mice, In vivo, Specifically, The HoxD9 protein is expressed in the early stages of mouse joint development, The human HoxD9 protein is also differentially expressed in the human cervical cancer cell line HeLa, and results in differential cofactor interaction, as it contains different activation domains, but is not expressed in the normal cervix and may thus play a role in tumorigenesis, but not in osteoarthritis patients, but not in that of normal mice, primarily in the articular cartilage, suggesting that HoxD9 may have a role in the pathology of arthritis, the HoxD9 protein interacts with the autoregulatory and cross-regulatory enhancers of the murine HoxB1 and human HoxD9 genes, the HoxD9 protein interacts with the human control region (HCR) of the HoxD9 gene, the HoxD9 protein is highly expressed in the synoviocytes of patients with rheumatoid arthritis (RA), thus inducing transcription of the HoxD9 promoter, The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HOX4, HOX4C, HXD9_HUMAN, Homeobox protein Hox D9, Hox 4, Hox 5, RP23 313J15, 2, 3, 10, homeobox D9
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHOXD9
Short nameHOXD9 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHOXD9 (Antibody to)
Alternative techniqueantibodies
Identity 5140
Gene HOXD9
Long gene name homeobox D9
Synonyms gene HOX4C HOX4
Synonyms gene name homeo box D9
Locus 2q31, 1
Discovery year 1990-06-15
Entrez gene record 3235
Pubmed identfication 1973146 1358459
Classification HOXL subclass homeoboxes
Havana BLAST/BLAT OTTHUMG00000132516

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