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HOXD9 Antibody, ALEXA FLUOR 350

HOXD9 Antibody, ALEXA FLUOR 350 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 350 Conjugated, HOXD9 Polyclonal Antibody
Also known asAnti-HOXD9 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenHOXD9
SpecificityThis is a highly specific antibody against HOXD9
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HOXD9
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Activation of HoxD9 depends on the structure of the target regulatory element, Furthermore, HoxD9 may be a multifunctional transcriptional regulator, HoxD9 transcripts are also detected in the synovial tissue of arthritic mice, In vivo, Specifically, The HoxD9 protein is expressed in the early stages of mouse joint development, The human HoxD9 protein is also differentially expressed in the human cervical cancer cell line HeLa, and results in differential cofactor interaction, as it contains different activation domains, but is not expressed in the normal cervix and may thus play a role in tumorigenesis, but not in osteoarthritis patients, but not in that of normal mice, primarily in the articular cartilage, suggesting that HoxD9 may have a role in the pathology of arthritis, the HoxD9 protein interacts with the autoregulatory and cross-regulatory enhancers of the murine HoxB1 and human HoxD9 genes, the HoxD9 protein interacts with the human control region (HCR) of the HoxD9 gene, the HoxD9 protein is highly expressed in the synoviocytes of patients with rheumatoid arthritis (RA), thus inducing transcription of the HoxD9 promoter, The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetHOXD9
Short nameHOXD9 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, HOXD9 (Antibody to)
Alternative techniqueantibodies
Identity 5140
Gene HOXD9
Long gene name homeobox D9
Synonyms gene HOX4C HOX4
Synonyms gene name homeo box D9
Locus 2q31, 1
Discovery year 1990-06-15
Entrez gene record 3235
Pubmed identfication 1973146 1358459
Classification HOXL subclass homeoboxes
Havana BLAST/BLAT OTTHUMG00000132516

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